NMDA receptor and bizarre autoimmune synaptic central neurological diseases
Certainly this time all my fame as a pioneer was not enough to introduce treatment and save the life of a very young child with NMDA receptor encephalitis. It was soon after the New Year in 2010. I was returning from Alacaniz, close to Teruel, in one of the rare times when I have been […]
The need for staging of amyotrophic lateral sclerosis
In this paper I will be refering in part to my experience of almost 40 years working with patients with amyotrophic lateral sclerosis, the last 12 with the ALS Functional Rating Scale, which I introduced in Brasil with Dr Jarise Gouvea in 2005. And the text will be based also on the paper “Is ALS […]
Inflammatory pathways in amyotrophic lateral sclerosis
A review and update in a few key studies in animals and patients of inflammation that draws ALS and MS much closer inclding in therapeutic possibilities
Sclerosis, apoptosis and inflammation in degenerative disease
In Latin and earlier in Greek sklera means something hard; in Medicine, something that has become hard to the point of being dead, and sclerotic is something that dies progressively and continuously, degenerates, and is replaced by tissue made up of collagen, elastic and reticular fibers. This is what happens after inflammation, different from the […]
